Laropiprant+nicotinic Acid
About Laropiprant+nicotinic Acid
Laropiprant+nicotinic Acid is used to treat dyslipidaemia, particularly in patients with combined mixed dyslipidaemia (characterised by elevated levels of LDL-cholesterol and triglycerides and low HDL-cholesterol) and primary hypercholesterolaemia (heterozygous familial and non-familial). Dyslipidemia is a condition characterized by an imbalance in lipid levels.
Laropiprant+nicotinic Acid contains Nicotinic Acid and Laropiprant. Nicotinic acid lowers LDL/bad cholesterol and triglycerides while increasing HDL/good cholesterol. Laropiprant helps reduce flushing, a common side effect of Nicotinic Acid. Together, Laropiprant+nicotinic Acid helps treat dyslipidemia and hypercholesterolaemia.
In some cases, you may experience some side effects like diarrhoea, dizziness, nausea, vomiting, upset stomach or heartburn, headache, and flushing. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects consistently.
Do not take Laropiprant+nicotinic Acid if you are allergic to any of its components. Consult your doctor before using Laropiprant+nicotinic Acid if you are pregnant or breastfeeding. Let the doctor know if you are taking any other medications and have any medical conditions, including peptic ulcer disease, arterial bleeding, unstable angina, diabetes, gout, liver or kidney problems and other pre-existing medical conditions to avoid potential interactions.
Uses of Laropiprant+nicotinic Acid
Medicinal Benefits
Laropiprant+nicotinic Acid is used to treat dyslipidaemia, particularly in patients with combined mixed dyslipidaemia (elevated levels of LDL-cholesterol and triglycerides and low HDL-cholesterol) and primary hypercholesterolaemia (heterozygous familial and non-familial). Laropiprant+nicotinic Acid contains Nicotinic Acid (lipid-modifying medicine) and Laropiprant. Nicotinic acid lowers LDL/bad cholesterol and triglycerides while increasing HDL/good cholesterol. Laropiprant helps reduce flushing, a common side effect of Nicotinic Acid. Together, Laropiprant+nicotinic Acid helps treat dyslipidemia and hypercholesterolaemia.
Directions for Use
- Laropiprant+nicotinic Acid can be taken with food or as advised by your doctor.
- Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
- Swallow Laropiprant+nicotinic Acid as a whole with a glass of water.
- Do not break, chew, or crush it.
Storage
Side Effects of Laropiprant+nicotinic Acid
- Dizziness
- Rash
- Pruritus (itching)
- Hives
- Upset stomach or heartburn
- Headache
- Tingling or numbness of the hands or feet
- Flushing
- Vomiting
- Nausea
- Diarrhoea
Drug Warnings
Laropiprant+nicotinic Acid is contraindicated in individuals with hypersensitivity to its ingredients, significant or unexplained liver dysfunction, arterial bleeding or active peptic ulcer disease. Inform the doctor if you have liver/kidney/thyroid problems, diabetes, heart problems, gout, low phosphorus levels, hereditary muscle disorder, had muscle problems during treatment with cholesterol-lowering medicines, are over 70 years old, or are due to undergo surgery. Please consult the doctor if you are pregnant or breastfeeding. Laropiprant+nicotinic Acid is not recommended for children below 18 years.
Drug Interactions
Drug-Drug Interactions: Inform the doctor if you are taking statins (atorvastatin, rosuvastatin), antibiotics (ketoconazole), antihyperlipidemic agents (lomitapide), anticoagulants (warfarin, coumadin), NSAIDs (aspirin), sedatives (midazolam), or antiplatelet agents (clopidogrel).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Inform your doctor if you have hyperglycemia, liver disease/hepatotoxicity, kidney disease, peptic ulcer disease, rhabdomyolysis, bleeding disorders, hyperuricemia, arterial bleeding or unstable angina.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid consumption of alcohol while taking Laropiprant+nicotinic Acid, as it may increase flushing (redness, warmth, itching, or tingling).
Pregnancy
consult your doctorThere is no data on the use of Laropiprant+nicotinic Acid in pregnant women. It has not been investigated for reproductive harm. The possible risk to people is unknown. Hence, Laropiprant+nicotinic Acid should not be used during pregnancy unless required.
Breast Feeding
consult your doctorIt is not known if Laropiprant+nicotinic Acid passes into breast milk. Please consult your doctor if you are breastfeeding.
Driving
cautionLaropiprant+nicotinic Acid may cause dizziness. Therefore, avoid driving or operating heavy machinery until you are fully alert.
Liver
unsafeLaropiprant+nicotinic Acid should not be used in patients with existing liver problems. Please consult your doctor if you have any concerns.
Kidney
cautionLaropiprant+nicotinic Acid should be used with caution in patients with renal insufficiency, as nicotinic acid and its metabolites are primarily excreted by the kidneys. Please consult your doctor if you have any concerns.
Children
unsafeLaropiprant+nicotinic Acid is not recommended for use in children under 18 years, as its safety and efficacy have not been established.
Habit Forming
Diet & Lifestyle Advise
- Focus on whole, nutrient-dense foods such as fruits, vegetables and whole grains.
- Hydrate adequately with plenty of water.
- Limit sodium intake.
- Nourish your heart with healthy fats by adding flaxseeds, walnuts, and olive oil to your diet.
- Practice regular physical activity by engaging in jogging or brisk walking.
- Quit smoking and limit alcohol intake.
Special Advise
Regular monitoring of cholesterol levels and blood tests is advised during treatment with Laropiprant+nicotinic Acid.
Patients Concern
Disease/Condition Glossary
Dyslipidemia: Dyslipidemia is a condition characterized by an imbalance in lipid levels, such as high LDL (bad cholesterol), low HDL (good cholesterol), or high triglycerides, leading to an increased risk of atherosclerosis and cardiovascular disease.
Hypercholesterolemia: Hypercholesterolemia is a condition marked by elevated cholesterol levels in the blood. It increases the risk of heart problems, such as heart attack or stroke.
FAQs
Laropiprant+nicotinic Acid is used to treat dyslipidaemia, particularly in patients with combined mixed dyslipidaemia (elevated levels of LDL-cholesterol and triglycerides and low HDL-cholesterol) and primary hypercholesterolaemia (heterozygous familial and non-familial).
Laropiprant+nicotinic Acid contains Nicotinic Acid and Laropiprant. Nicotinic acid lowers LDL/bad cholesterol and triglycerides while increasing HDL/good cholesterol. Laropiprant helps reduce flushing, a common side effect of Nicotinic Acid. Together, Laropiprant+nicotinic Acid helps treat dyslipidemia and hypercholesterolaemia.
Avoid consuming alcohol or hot drinks and eating spicy food near the time of taking Laropiprant+nicotinic Acid to lower the chance of flushing.
The side effects of Laropiprant+nicotinic Acid include diarrhoea, dizziness, nausea, vomiting, rash, pruritus (itching), hives, upset stomach or heartburn, headache, tingling or numbness of the hands or feet, and flushing. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects consistently.
Laropiprant+nicotinic Acid may cause dizziness as a common side effect. Therefore, avoid driving or operating heavy machinery until you are fully alert.
Do not discontinue Laropiprant+nicotinic Acid without consulting the doctor, as your cholesterol problem may return. To treat your condition effectively, complete the course of treatment as prescribed.
